Based on our Second Sight Medical Products, Inc. EYES stock recorded 15/30 (50%) green days with 10.64% price volatility over the last 30 days. According to our technical indicators, the current sentiment is Bullish while the Fear & Greed Index is showing 39 (Fear). shares will drop by -2.05% and reach $ 4.05 per share by October 29, 2022. Published September 23, 2022.According to our current EYES stock forecast, the value of Second Sight Medical Products, Inc. Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration. Krzysztof Palczewski Henri Leinonen Taylor Nakayama, Julia R. The research was funded by the National Institutes of Health, the Department of Veterans Affairs and the Research to Prevent Blindness foundation. Kiser, who holds a joint appointment in ophthalmology, is a member, Center for Translational Vision Research. Philip Kiser, associate professor of physiology and biophysics, an expert on visual cycle biochemistry, helped lead the group. Palczewski, director of the Center for Translational Vision Research, is renowned for his work on retinoids and the visual cycle. Gandhi and first author Carey Huh, PhD, who initiated the project, teamed with Krzysztof Palczewski, Distinguished Professor of ophthalmology. “This new paradigm could aid in the development of retinoid therapies to more completely rescue the central visual pathway of adults with this condition.” “Whenever you have a discovery that breaks with your expectations about the possibility for the brain to adapt and rewire, it teaches you a broader concept,” Gandhi said. “The fact that this treatment works so well in the central visual pathway in adulthood supports a new concept, which is that there is latent potential for vision that is just waiting to be triggered.”Īccording to the news release, the finding expand a range of research possibilities. “The restoration of visual function at the level of the brain was much greater than expected from the improvements we saw at the level of the retinae,” Gandhi said in the release. However, Gandhi noted in the news release that what was even more mind-blowing was that the signals coming from the same-side eye pathway activated five-fold more neurons in the brain after the treatment and this impressive effect was long-lasting. “Immediately after the treatment, the signals coming from the opposite-side eye, which is the dominant pathway in the mouse, activated two times more neurons in the brain.” “The central visual pathway signaling was significantly restored in adults, especially the circuits that deal with information coming from both eyes,” Gandhi said in the news release. Working with rodent models of LCA, the collaborators were surprised by what they found. Until now, scientists believed that the brain must receive those signals in childhood so that central circuits could wire themselves correctly. It’s in the central circuits of the brain where visual perception actually arises.” It starts in the eye, which sends signals throughout the brain. “Seeing involves more than intact and functioning retinae. Gandhi is a fellow of UCI’s Center for the Neurobiology of Learning and Memory and a member of the Center for Translational Vision Research. “Frankly, we were blown away by how much the treatment rescued brain circuits involved in vision,” said Sunil Gandhi, professor of neurobiology and behavior and the corresponding author. The UCI team wanted to find out if the treatment could make a difference for adults who have the condition. The university noted that the researchers found that by administering chemical compounds that target the retina, called synthetic retinoids, they could restore a notable amount of vision in children with LCA. The condition, which stems from mutations in any of over two dozen genes, causes degeneration or dysfunction in the retina’s photoreceptors. The term refers to a group of inherited retinal diseases distinguished by severe visual impairment at birth. 1Īccording to a news release, the team was examining treatment for Leber congenital amaurosis, known as LCA. ![]() ![]() The finding that the adult brain has the potential to partially recover from inherited blindness comes from a collaboration between researchers in the University of California, Irvine School of Biological Sciences and the School of Medicine. A discovery about how some visually impaired adults could start to see offers a new vision of the brain’s possibilities.
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